Category: reality of race

Race, Sex, Trump, Durocher

In der news.

Not an incel.  Good to see that all of the Joan of Arcs out there are properly rewarding only the most high-quality male biological specimens with abundant sexual access!  After all, we only want high-IQ geniuses, producing the most exquisite cultural artifacts and the most important discoveries and inventions for human progress, to be thus rewarded.

When we need to save “Black bodies,” then race suddenly exists, and has a biological basis.

See comment # 208 in response to Durocher. None of those comments are from me, by the way, in case anyone was wondering. There are others willing to point out Durocher’s unrelenting mendacity. There is no line drawn in Europe separating the areas of absolute purity from those exhibiting highly admixed cringing subhumans.  Further, as my posts about ancestry testing have demonstrated, you can model any group – or individual – as combinations of other groups, if for some reason you wanted to do so. In the early days of population genetics, it was all about modeling the European genepool as a mix of Asian and African; in the paper Durocher ejaculates about, we see a supplementary data table modeling populations as mixes of German, Saharawi, and Qatari. Only an idiot who thinks Ostara was a scientific journal would take any of that at literal face value, without nuance.

Trump the HBDer.  Getting more East Asian females in America will be a boon to two groups of White deviants.  First, sublimated pedophiles can indulge themselves with adult Asian females with no legal sanction.  Pederasts benefit also. Since there is minimal phenotypic difference between an adult Asian female and a pre-pubescent boy, sublimated pederasts can avoid legal and societal sanctions and indulge their predilection for man-boy love with adult Asian females.  A win-win, I suppose.

Meanwhile, Trump the White-hating criminal traitor wants to replace native professionals with an Asian overclass.  After all, there are no native geniuses, right Don?  Well, in the Trump family, that’s certainly true.

Hey, Pelosi, when are you going to impeach Trump, who is CLEARLY guilty of obstruction of justice?  Impeach, trial by Senate, indictment, conviction for the CRIME of obstruction of justice, and then time spent in the prison infirmary to repair certain injuries sustained while having intimate conversations with fellow inmates.

IMPEACH TRUMP!

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More on Cancer Cell Lines

Race, race, race.

Read here.  Excerpts, emphasis added:

Assessing the role of ancestry-associated genetic variations in disease etiology is further complicated by the recent admixture that characterizes various populations of the world (24). Hence, an individual’s ancestry can be described by quantifying the proportion of the genome derived from each contributing population (global ancestry). Heterogeneity is also observed locally in the genome, as variability is observed in the ancestral origins of any particular segment of chromosomes (local ancestry; ref. 25). Ultimately, genetics plays a role in the biological characteristics of a cancer in the form of both germline variation and somatic alterations. Further research is needed to determine the extent to which genetic differences align with ancestral genetic changes (26).

Cell lines reported as “African” or “Black” clustered with African-American populations in 81.6% of the cases, emphasizing the ambiguity of the existing nomenclature. In fact, the proportion of the genome inferred to be of European origin in these cell lines averaged 18.32% (ranging from 0% to 95.09%). Another type of ambiguity concerns the cell line Hs 698.T labeled as originating from an “American Indian,” which clusters with populations of South Asia, suggesting an origin in India rather than from a Native/Indigenous American individual. A total of 26 cell lines were reported as Caucasian but clustered genetically with other populations including African (n = 2), African American (n = 6), East Asian (n = 1), Hispanic/Latinos (n = 16), and South Asian (n = 1). Interestingly, 89% of the cell lines identified as Hispanic/Latino from admixture patterns and clustering are reported as “Caucasian.” Several groups have reported a concordance between self- or observer-reported belonging to major racial/ethnic groups (141–143). However, these categories do not capture the inherent heterogeneity of admixed populations (144–147). What appears as inconsistencies in self-report and genetic data may result from individuals having limited knowledge of their ancestral origins, or culturally identifying to an ethnic group that is not representative of one’s admixture proportions (18). Sociological, behavioral, and biological factors that underlie race, ethnicity, and ancestry are likely to interact (148). Consequently, from a biomedical research perspective, both self-reports of race/ethnicity group as well as genetically determined clustering and admixture are expected to be relevant in understanding disease susceptibility, and ultimately, the causes of health disparities (18, 148, 149).

Note the last phrase.  Also, importantly, there is misclassification.  Given that people are not always accurate about their own self-reported ancestry, what can we say about the ancestry testing companies that use customer samples to inflate their pathetically limited parental/reference population datasets?

Also consider Figure 1 in the paper. It looks to me like the cancer cell lines exhibit more admixture than the actual human population samples. At the very least,there are observable differences in ancestral proportions. Some of that of course is simply the well known admixture in “African Americans,” but what about the other populations?  That could be due to the misclassification mentioned above, there are of course issues about sample size, and concerns over how accurate the ancestry testing is. Cancer cell lines also tend to have high mutation rates, reflecting the situation in the tumor of origin. However, even with all those caveats, can we consider the possibility that increased admixture is associated with a higher cancer risk; hence, cancer cell lines show more admixture because cancer patients are on average more admixed than is typical of the general  population?  Given how prevalent cancer is, the differences are not great, as we are dividing populations in two relatively similar “chunks” (the difference being cancer vs. non-cancer); but still, if there is going to be any differences between the two “chunks” – perhaps the cancer “chunk” exhibits more admixture than the non-cancer “chunk?” Anyone willing to test the hypothesis?  Or, we can consider the more general hypothesis of statistically significant differences in ancestry between cancer vs. non-cancer for each population group (regardless of admixture, or which group has more admixture, etc.).  

Race and Skin Properties

We are NOT “all the same.”

See this about skin properties.

See this. Excerpts below, emphasis added:

TABLE 2
Ethnic groups and highlighted key differences in facial structure

ETHNIC GROUP HIGHLIGHTED FACIAL STRUCTURE DIFFERENCES

Caucasian face Narrower nasal base and larger tip projection, intercanthal widths identical to the African face, lips with less volume

East Asian face Weaker facial skeletal framework, wider and rounder face, higher eyebrows, fuller upper lid, lower nasal bridge with horizontally placed flared ala, flatter malar prominence and midface, more protuberant lips, and more receded chin

Latino/Hispanic face Increased bizygomatic distance, bimaxillary protrusion, broader nose, broad rounded face, and a more receded chin

African-American face  Broad nasal base, decreased nasal projection, bimaxillary protrusion, orbital proptosis, increased soft tissue of the midface, prominent lips, and increased facial convexity

I don’t like the “Caucasian” category that bins MENA folks with Europeans, but, putting that aside, note the important and fundamental differences in facial structure between the major racial groups.

Let’s consider the HBDers’ favorite continent – Asia:

The Asian face. The Asian population is quite diverse. Literature is limited and has typically focused on a particular ethnicity or a small number of outcomes in several Asian populations, mostly from East Asia. Although literature is limited and without a full, thorough comparison, there are many differences that have been noted. East Asians typically have less wide mouths, elongated intercanthal width, and wider lower nasal margins.38 Studies suggest that Asians have a weaker facial skeletal framework, which results in greater gravitational soft-tissue descent of the mid-face, malar fat pad ptosis, and tear trough formation. It has also been proposed that the facial structure of Asians is similar to that of an infant, including a wider and rounder face, higher eyebrow, fuller upper lid, lower nasal bridge with horizontally placed flared ala, flatter malar prominence and midface, fuller and more protuberant lips, and more receded chin.39,40

Note the neotenic aspects of the Asian phenotype East Asian facial structure is similar to that of an infant. Also note that the higher body fat percentages of East Asians is also infant-like. This supports the idea that Yellow Fever has an underlying pedophilia predisposition to it. It is perhaps not surprising that a leading “movement” figure with an East Asian wife has publicly questioned why child porn should be illegal. Note the “frog faced” characteristics of the East Asian facial phenotype as well.

Despite the large South East Asian population, limited studies have been conducted assessing facial structure. Overall, there is tremendous variability over such a large geographic area and diverse population. Despite this, it is generally accepted that those from the Indian subcontinent share more Caucasoid than Mongoloid anatomical traits of the skull and face. 

Here we see the authors binning South Asians with East Asians, which is just as (if not more) racially stupid as binning Europe with MENA:

Compared to East Asians, South Asians typically possess eyelids that are on a more highly exposed platform, have well-developed nasal bridge with tip projection, and have comparatively darker and more uneven skin tones. Also, South Asians tend to have fuller lips and higher cheek bones with more buccal fat, often giving the lower cheek a more rounded contour. These features often provide physical support for the aging face more so than other Asian ethnicities.

The bottom line: Race is real and is written on all of our faces.  Live with it.  Reality doesn’t care about your politically correct feelings.

We Are Not All the Same

Genes, Race, IQ, and disease.

One refutation of Lynn, and three papers with emphasis added.

Refuting Lynn, refuting the Alt Wrong/Alt Yellow.  Amren weeps.

Read here.

BACKGROUND:
Although cell lines are an essential resource for studying cancer biology, many are of unknown ancestral origin, and their use may not be optimal for evaluating the biology of all patient populations.
METHODS:
An admixture analysis was performed using genome-wide chip data from the Catalogue of Somatic Mutations in Cancer (COSMIC) Cell Lines Project to calculate genetic ancestry estimates for 1018 cancer cell lines. After stratifying the analyses by tissue and histology types, linear models were used to evaluate the influence of ancestry on gene expression and somatic mutation frequency.
RESULTS:
For the 701 cell lines with unreported ancestry, 215 were of East Asian origin, 30 were of African or African American origin, and 453 were of European origin. Notable imbalances were observed in ancestral representation across tissue type, with the majority of analyzed tissue types having few cell lines of African American ancestral origin, and with Hispanic and South Asian ancestry being almost entirely absent across all cell lines. In evaluating gene expression across these cell lines, expression levels of the genes neurobeachin line 1 (NBEAL1), solute carrier family 6 member 19 (SLC6A19), HEAT repeat containing 6 (HEATR6), and epithelial cell transforming 2 like (ECT2L) were associated with ancestry. Significant differences were also observed in the proportions of somatic mutation types across cell lines with varying ancestral proportions.
CONCLUSIONS:
By estimating genetic ancestry for 1018 cancer cell lines, the authors have produced a resource that cancer researchers can use to ensure that their cell lines are ancestrally representative of the populations they intend to affect. Furthermore, the novel ancestry-specific signal identified underscores the importance of ancestral awareness when studying cancer.

Racial genetic differences mean that results obtained with cancer cell lines from one race may very well be NOT applicable to other races.  There are indeed racial differences in gene sequences and gene expression, with clinically significant implications for patients.

Read here.

BACKGROUND:
We examined racial differences in the expression of eight genes and their associations with risk of recurrence among 478 white and 495 black women who participated in the Carolina Breast Cancer Study Phase 3.
METHODS:
Breast tumor samples were analyzed for PAM50 subtype and for eight genes previously found to be differentially expressed by race and associated with breast cancer survival: ACOX2, MUC1, FAM177A1, GSTT2, PSPH, PSPHL, SQLE, and TYMS. The expression of these genes according to race was assessed using linear regression and each gene was evaluated in association with recurrence using Cox regression.
RESULTS:
Compared to white women, black women had lower expression of MUC1, a suspected good prognosis gene, and higher expression of GSTT2, PSPHL, SQLE, and TYMS, suspected poor prognosis genes, after adjustment for age and PAM50 subtype. High expression (greater than median versus less than or equal to median) of FAM177A1 and PSPH was associated with a 63% increase (hazard ratio (HR) = 1.63, 95% confidence interval (CI) = 1.09-2.46) and 76% increase (HR = 1.76, 95% CI = 1.15-2.68), respectively, in risk of recurrence after adjustment for age, race, PAM50 subtype, and ROR-PT score. Log2-transformed SQLE expression was associated with a 20% increase (HR = 1.20, 95% CI = 1.03-1.41) in recurrence risk after adjustment. A continuous multi-gene score comprised of eight genes was also associated with increased risk of recurrence among all women (HR = 1.11, 95% CI = 1.04-1.19) and among white (HR = 1.14, 95% CI = 1.03-1.27) and black (HR = 1.11, 95% CI = 1.02-1.20) women.
CONCLUSIONS:
Racial differences in gene expression may contribute to the survival disparity observed between black and white women diagnosed with breast cancer.

Health disparity differences in outcome for breast cancer in White vs. Black women have a genetic basis.

Read this.

Age at menarche (AM) and age at natural menopause (ANM) define the boundaries of the reproductive lifespan in women. Their timing is associated with various diseases, including cancer and cardiovascular disease. Genome-wide association studies have identified several genetic variants associated with either AM or ANM in populations of largely European or Asian descent women. The extent to which these associations generalize to diverse populations remains unknown. Therefore, we sought to replicate previously reported AM and ANM findings and to identify novel AM and ANM variants using the Metabochip (n = 161,098 SNPs) in 4,159 and 1,860 African American women, respectively, in the Women’s Health Initiative (WHI) and Atherosclerosis Risk in Communities (ARIC) studies, as part of the Population Architecture using Genomics and Epidemiology (PAGE) Study. We replicated or generalized one previously identified variant for AM, rs1361108/CENPW, and two variants for ANM, rs897798/BRSK1 and rs769450/APOE, to our African American cohort. Overall, generalization of the majority of previously-identified variants for AM and ANM, including LIN28B and MCM8, was not observed in this African American sample. We identified three novel loci associated with ANM that reached significance after multiple testing correction (LDLR rs189596789, p = 5×10⁻⁰⁸; KCNQ1 rs79972789, p = 1.9×10⁻⁰⁷; COL4A3BP rs181686584, p = 2.9×10⁻⁰⁷). Our most significant AM association was upstream of RSF1, a gene implicated in ovarian and breast cancers (rs11604207, p = 1.6×10⁻⁰⁶). While most associations were identified in either AM or ANM, we did identify genes suggestively associated with both: PHACTR1 and ARHGAP42. The lack of generalization coupled with the potentially novel associations identified here emphasize the need for additional genetic discovery efforts for AM and ANM in diverse populations.

There seems to be genetic differences underlying reproductive lifespan in women of different races.  I hypothesize that Negro females would tend to possess variants promoting earlier reproduction.  Blacks and Hispanics have earlier puberty than Whites.

Breaking Free of the Zoo

And other news.

Read this.  Another installment of the evaluation of Yockey’s racial ideas in the light of rational scientific racial reality.

Derbyshire weeps.

Question – can we put ugly, plastic-surgery-enhanced, semi-retarded, egotistical, vapid, yeast-infested, hit-the wall-head-on, ditzy airheads all on an island?  The Island of Misfit Turds?

All together now….he’s the last chance for White America!

So, since White America is all out of chances, we can expect the Quota Queens to close up shop, right?  No more panhandling?  Retire the tin cup and join the great unwashed and become another cog in the machine.  Join the crowd boys (including Mr. Coulter as well).

Don’t you know that Trump’s entire Presidency is just a bunch of jackass tweets?  The Alt Right President indeed!  It’s about that time for Roissy to post a gif of Trump strutting like Vince McMahon; after all, that’s what being an effective leader is all about, no?

Of course America is last.  Trump is a fraud and always has been, which all you guys would have known if you’ve been reading EGI Notes, instead of marinating in the affirmative action stew of not-so-bright, hopelessly naïve Quota Queens (and Kings – don’t want to leave Coulter out).

Your God Emperor is laughing at all you suckers.

And you all deserve it.

Rethinking Horizontal Race

Yockey.
More commentary on this and related topics will be forthcoming, as a major focus of my work will be to formulate a scientifically-informed Yockeyism that incorporates Salterism into Yockeyist thought (and vice versa?).
While I will still deconstruct the “movement” when appropriate, a constant monitoring and critiquing of every single stupidity of Der Movement is a waste of time, for many reasons, not the least of which is that the “movement” is not redeemable, and all of the Type I Nutzis are never going to change their ways. It is time for the Type IIs to plan on making their stand.

Friday Follies

Race and Der Movement.  In all cases, emphasis added.

The average reader may not know this, but Hela cells are often a big problem in the biomedical cell culture laboratory environment – the cells are aggressive and invasive (surprise!), resulting in significant cross-contamination of other, more unique and valuable, cell cultures.

However, 20 years after Henrietta Lacks’ death, mounting evidence suggested that HeLa cells contaminated and overgrew other cell lines. Cultures, supposedly of tissues such as breast cancer or mouse, proved to be HeLa cells. We describe the history behind the development of HeLa cells, including the first published description of Ms Lacks’ autopsy, and the cell culture contamination that resulted.

Many labs therefore want nothing to do with that cell line, in order to preserve the integrity – dare we say “purity?”- of their other cell culture stocks. Interesting analogies can be made to other, broader, societal, situations.

Good news.

I have two points to make about this.

First, we should not be surprised that Fukuyama preaches to Whites memes that will inevitably lead to their destruction.  As EGI Notes tells you time and time again: The existential meaning of Asians is hatred of Whites. 

Second, we see Greg once again engaging in the most outrageous and dishonest gaslighting – this time trying to convince you that WWI and WWII were not due to petty ethnonationalism, but a lack thereof.

You see, “WWI was not a war of nations, but of empires.” The empires did it!  It were all the South Asians of India, the Algerians of North Africa, the Egyptians, the Negroes of German South West Africa, the Siberians – they were the ones pushing the honest and humble ethnonationalists of Great Britain, France, the Turkish Ottomans, Germans, and Russians into war. It had nothing at all to do with the rise of German power, the British desire to thwart that power, French fear and hatred of Germany, Russia’s desire for power and influence and their ethnosubracial pan-Slavism, no sir!  It was dem dere empires dat done it, lordy yes!

At this point, the ethnonationalist riposte would be: Austria-Hungary!  Empire!  The Archduke!  The Serbs!  Empire caused the war!  

Does anyone really believe that the underlying cause of WWI was the assassination of some useless aristocratic parasite?  No – the great powers of Europe, which did NOT include the “sick men” of Austria-Hungary and the Ottomans – were primed for war, wanted war – because of their selfish, petty nationalist (or subracial-ethnic-cultural-petty nationalist in the case of Russia) interests. The young Europeans who cheered for war and volunteered in droves in 1914 did not do so because of “empire” or because of “the Archduke.” They did so out of national pride and because of a petty nationalist animus toward their fellow Europeans.

Therefore, the assassination was merely an excuse. The Austrian tail did not wag the German dog; the Serbian tail did not wag the Russian dog, and the British and French didn’t care one whit about “national determination” (they were “empires,” no?).  It was all an excuse for a petty nationalist war that was not caused by empires but that ultimately caused the end of those empires.

And, oh, yes, WWII occurred “because the ethnic boundaries were not properly drawn after WWI.” Right? Very good.  By that logic, Greg, your Saint Adolf should have stopped after uniting with Austria and getting the German part of Czechoslovakia.  Or are you going to tell us the invasion of Poland was really about the “Polish corridor?”  Yeah…and I have a bridge to sell you connecting Manhattan and Brooklyn. Hitler had his lebensraum aims that were completely ethnonationalist, or at least Germanic/Nordicist. Hitler wanted land from the Slavs and wanted revenge against the French. There was also an honest fear and loathing of Soviet communism – although that didn’t stop the Nazi-Soviet pact to destroy Poland.  The British were playing their usual game of preventing a continental power from emerging, and, again, the French feared and hated the Germans. And it was the petty nationalism of the British and French that prevented a pan-European alliance with Germany and Italy to destroy Soviet communism. The USSR had its own agenda, both of power politics and Marxist expansionism. Tell me – where in all of this was the war being caused by pan-European ideals?  By multi-national states?  And the only real link to “empire” here was the German (and Italian and Japanese) national desire for empire.  And did Great Britain fight the war “to save the empire?”  Hardly.  Hitler was willing to guarantee the existence of the British Empire, which he admired.  The British just wanted to destroy Hitler and Nazi Germany.  The same old “grand strategy” of Great Britain – which lost them their empire and resulted in the homeland being reverse colonized by the Third World.  Ethnonationalism!  Snug in your hobbit hole!

The facts – the clear historical facts – demonstrate that petty nationalism, ethnonationalism, caused both World Wars and wrecked the White World, and to argue otherwise, and to try and shift the blame to the opponents of petty nationalism, is an even greater act of outrageously despicable dishonesty than the previous Gaslighting Greg act of blaming the failure of WN 2.0 on those who eschewed and opposed WN 2.0.

I have no idea what happened to this guy Johnson; I think his hatred of Richard Spencer has unhinged his mind.

A commentator responds to Johnson:

Now, while I strongly believe in the practical value of ethnic homogeneity this is not always feasible. Also a myriad of small but homogeneous states without a certain supra-national structure will render them indefensible against the Asian Empires – Russia and China! And these two do know how to genocide. So again, an effete bureaucrat of EU Commission is a better choice (and probably the only one acceptable currently) in order to maintain the peace between not perfectly homogeneous states but also to prevent the Asian Empires expansion in Europe.
This structure was working in a certain degree until Angela Merkel blown it up by opening unilaterally the borders of Germany.
My hope is for a Union of all white peoples (Europe, US, Canada, Australia, New Zealand and South Africa and a proper part of South America) each people living in its own state based on its historical right (defined genetically and culturally), but organized in a supra national white states entity; expulsion of all non-European populations and individuals, including the mixed race individuals. Common defense, common positions regarding the rest of the world. Free internal markets. Free circulation of ideas and goods. Limited people circulation.

That’s OK as far as it goes, but he should have critiqued Johnson’s initial premises.  For an ethnonationalist to blame WWI and WWII on “empires” and “multi-national states” is chutzpah of an order to make Dershowitz proud.  It’s disgusting.

Then we have the vile hypocrite Roissy, who laments this story, while he has previously bragged about one of his girlfriends offering “do you want to put it in my ass?”  I guess the blowback from the unbridled nihilistic sexual hedonism the gamesters preach is not always to their liking.  Then we have the hypocrisy of “game” advocates always throwing their “Christianity” in our face, as if their lifestyle is in any way even remotely compatible with even the most modern dilution of authentic Christian belief.  I can honestly say that in my entire life I have never met even one genuine Christian; as Nietzsche wrote – there was only one Christian and he died on the cross.

“Based” Tulsi.  Gee…the Woman on Green Pepe Syndrome hit a snag real fast, eh?

Wrong, wrong, they’re always wrong.

Leftist lies on race, this from The NY Times, a racist media outlet who hired White-hating genocidal Asian bigot (or, more simply – “Asian”) Sarah Jeong:

People who live in a place today often bear no genetic resemblance to people who lived there thousands of years ago, so the idea that something in your blood makes you meaningfully Spanish is absurd.

Hmm… is that why Otzi the Iceman is genetically most similar to modern Europeans?  Is that why ancient DNA analyses typically puts those samples closest to their modern day counterparts than to, say, people halfway across the globe?  How about a bet?  I’d say that the genomes of ancient Britons are genetically more similar to the modern English than they are to, say, Nigerians.  If I’m wrong, I’ll admit it right here.  If I’m right, the author of the NY Times piece will agree to resign his position and get a swastika tattooed on his forehead.  Fair bet?