Category: reality of race

Eternity Lost: Racial Diversity and the Fermi Paradox

Paper.

A journal that shall go nameless refused to publish that – without even sending it out for peer review – with the justification that it was “too speculative.” You can decide for yourself whether you believe that excuse, or whether you believe the refusal was for another reason.

And, yes, I know, the paper is too positive toward the HBD perspective and certain HBDers.  However, if the paper had been sent out for review, who would have been likely reviewers?  And, after all, what I cite in that paper are those aspects of HBD which to me reflect reality. There are, after all, differences in intelligence and behavior between the major racial groups, differential birthrates are real, dysgenic trends are real, spiteful mutations are real (just look at the HBDers themselves), etc. I don’t promote the worst aspect of HBD, their lies and distortions.

In any case, the paper is, in essence, a fully fleshed out version of the blog post.

Abstract

The Fermi paradox asks – if aliens and advanced alien civilizations exist, then where are they?  Why have they not visited us? Why have we found no evidence of the existence of alien civilizations? The implication is that sentient intelligent aliens do not exist, and thus their civilizations do not exist. One possibility is that they existed in the past but do not exist now; another possibility is that they have never existed. In either case, something inhibits the development or maintenance of a detectable (by humans) space-faring alien civilization. Here I review several major explanations for the Fermi paradox and then propose a novel solution that focuses on racial diversity, racial differences, and civilizational collapse.  It is typical to envision sentient alien species as monolithic populations, portrayed as monoracial and phenotypically fungible. What if this assumption is incorrect?  Perhaps racial diversity is the rule among sentient species; thus, highly divergent human racial types find their counterparts in significant racial variability among alien peoples inhabiting worlds unknown. I further propose a Gresham’s law of universal racial diversity: the more intelligent and productive races of any sentient species will tend to be demographically outcompeted by those less intelligent and accomplished.  Other disruptive social pathologies may also occur concomitant with increased local intra-species diversity. The threshold of technological competence for a space-faring alien civilization would no longer obtain as the races and cultures capable of maintaining that civilization are replaced by those incapable.  Therefore, no such civilizations are detected.

Keywords:  Fermi paradox, aliens, civilization, race, intelligence

Introduction

The so-called “Fermi paradox”    asks – if aliens and alien civilizations exist, why haven’t we discovered any yet? Where are they? Why have not we been visited (assuming for the moment that UFOs are not evidence of visitation that has already occurred)?  Assuming that evolution to a Type III civilization on the Kardashev scale is an assumed outcome of an ever-growing and evolving alien civilization  , where are they?  Where are the self-replicating alien probes3  that we are told should be infesting galactic space; where are the “flying saucers landing on the White House lawn?” It is possible that we are alone? Shouldn’t alien civilizations exist, given the Drake equation  and the numerous possible habitable alien words that exist? Where is everyone? The implication is that intelligent aliens and their civilizations do not exist, that they do not exist now or that they have never existed. A weaker interpretation would be that something inhibits the development of a detectable space-faring higher civilization, even though there may well be intelligent extraterrestrial life, or at least has been such in the past.

In a 2015 essay, Robert Gray argued that the “paradox” as popularly perceived is neither Fermi’s nor is it truly a paradox.  Apparently, Fermi informally broached the subject during a 1950 Los Alamos lunch, with the focus more on the feasibility of inter-stellar travel than on the existence of intelligent extraterrestrial life with a technologically advanced civilization1.  In 1975, Michael Hart more formally suggested that the lack of alien visitors meant that there is no intelligent alien life in our galaxy, with various counter-arguments being dismissed2. This idea was extended by Frank Tipler, who argued in 1980 that alien intelligences would have constructed self-replicating machines (e.g., probes) that would have spread throughout the universe, and the absence of such probes suggests that no intelligent alien life exists in the universe; Man is truly alone3. Besides stating that the paradox is properly ascribed to Hart-Tipler rather than Fermi, Gray further argues that it is not a paradox at all, because the Hart-Tipler arguments are based on a number of assumptions that may not be true. Is inter-stellar travel feasible? Would the galaxy be quickly filled? Would the Earth be colonized? Would this scenario be stable over time? These and other questions are assumed premises which if incorrect would weaken the ”Fermi paradox” arguments1.

Gray makes valid points, and in general I agree with his arguments. However, for the sake of simplicity, and to invoke popular perception, I will continue to use the term “Fermi paradox” although it is to be understood to more properly describe Hart-Tipler arguments. In addition, while the existence of the “paradox” depends on a number of questionable premises, since “they” are apparently not here, it is useful to accept the existence of the paradox and examine explanations given in the literature, leading to my own thesis.

Several Explanations 

Among the more recent hypotheses for the Fermi paradox, and in line with certain sociopolitical biases toward “green” outlooks, are those revolving around “sustainability.” Prominent among these approaches is the interesting speculative work of Wong and Bartlett, which builds upon a variety of other studies to formulate one potential solution to the Fermi paradox4.

In this analysis, planetary civilizations are considered akin to global cities, and cities are assumed to inevitably suffer from “superlinear scaling” causing demand for resources to outstrip supplies. While technological innovation can temporarily hold off collapse, eventually the ever-decreasing intervals between crises leads to systematic collapse occurring before a “reset” can be arranged.  There may be an eventual revival, but any subsequent growth-oriented civilization would suffer the same fate and therefore no planetary civilization would make the leap to the point in which it becomes inter-galactic and thus directly makes its presence known to other civilizations. The authors further speculate that such a civilization has an alternate pathway, which they term “homeostatic awakening,” which can be considered the politically “green” approach of valuing long-term homeostatic stability over that of growth.  Although this latter model may avoid collapse, it would also likely prevent the development of a technological civilization advanced enough to travel to other star systems.  Hence, both models – growth and collapse vs. stable “green’ sustainability – would prevent the development of a civilization that would make tis presence known to an extent as to eliminate the Fermi paradox.

There are a number of assumptions built into this hypothesis, and the authors correctly cite some of them in their Discussion.  Is the “superlinear” city model always correct and does it apply universally to larger biological groups, both on Earth and among putative alien civilizations? Will a “global city” linked by information processing rather than physical geographical proximity reflect the same limitations of physical city growth?  Is it always true that technological resets are temporary and limited? Isn’t it possible that a technological fix, or set of fixes, would allow a civilization to have access to practically infinite energy resources?  Could limitations of civilizational growth, such as those that are computational and memetic and not only physical related (energy and physical resources as well as disease), be self-correcting in certain alien cultures?

I also ask – is it possible alien civilizations, using technological breakthroughs that we do not understand, solve the problem of inter-galactic space travel even at a level of civilization not much greater than our own? Thus, instead of going through a slow phase of development of space travel, starting as humans have with chemical reaction engine rockets travelling short distances in space, could some alien civilization stumble upon “exotic” approaches to bridge the gulfs of space early in their space-faring journey? This possibility would “short-circuit” the collapse scenario and allow for inter-stellar travel by a civilization at the same stage as ours, albeit one “lucky” enough to have solved the technical problems of a space-faring culture sans an accompanying very high level of civilizational development.

Wiley5 has considered a number of these issues.  He agrees with Tipler that the seeming absence of self replicating space-probes (SRPs) is a problem, given that he dismisses arguments made against the feasibility and relevance of SRPs.  However, he does cite the idea that perhaps we simply haven’t been able to identify SRPs that actually have entered our solar system (although this would argue for a lower limit for SRP numbers; if we were overwhelmed by them they would be hard to miss – although I suppose they can be very small, even microscopic)5.  Further, the SRPs from alien civilizations outside our galaxy simply may not be able to reach us across the vast gulf of inter-galactic space5.  Perhaps extra-galactic alien civilizations are more likely than those in our own galaxy. He considers “Percolation Theory” as having promise, re: the Fermi paradox; thus, a sufficient number of non-colonizing colonies would block the expansion of the colonizing ones, putting a natural brake on expansion5. Wiley also considers and critiques a number of social collapse scenarios before introducing the idea of “interstellar transportation bandwidth.”  Thus, there may be limitations on how many individuals can be transported across space in a given time frame. This may shield civilizations from contamination of the problems from elsewhere, making expansion more robust and making the Fermi paradox more problematical. If expansion is more protected and robust then where is everyone? On the other hand, the same bandwidth problem can limit expansion of biological aliens and thus explain perhaps why we haven’t encountered anyone yet.  Note that this explanation assumes that a space-faring civilization has been established; in contrast, my alternative explanation (below) would explain why such a civilization may never come into being in the first place.

Another work  invoked the idea of the “astrobiological phase transition” mediated by “global regulation mechanisms” such as gamma ray bursts. The astrobiological history of the Milky Way could therefore be divided into three phases, each separated by a transition.  First, there was an early period devoid of life. Second, there was (or still is) a “disequilibrium” period in which life evolves, but global regulation mechanisms such as gamma ray bursts destroy sentient alien species before they reach the high technological level required of a space-faring civilization. Finally, once gamma ray bursts and other catastrophic events significantly decrease in frequency in an aging galaxy, a third “equilibrium” phase is reached in which a dominant space faring technological civilization has the time to safely develop. If humans are in late period II or early period III then not enough time has elapsed between catastrophic “resets” to allow the development of an alien civilization that we could encounter. In the future, in later period III, things would be different and at least one space-faring civilization would exist to make its presence known. This thesis makes several testable predictions and has been amenable to computer modeling7.

Some of the abovementioned scenarios may be plausible. Astrobiological phase transition seems to me to be particularly promising.  However, none of these explanations are proven and, more to the point, are not all completely incompatible with each other. Even if these scenarios have validity for at least some putative alien civilizations, aren’t there also other possibilities, heretofore ignored, that also can be considered?  Is there an alternative explanation that has heretofore gone unmentioned, perhaps in part because it is too controversial and “politically incorrect?”

An Alternative Explanation

I will now present an alternative explanation for the Fermi paradox, which fits in with the “societal collapse” set of possibilities, albeit with a novel mechanism proposed.

Popular conceptions of aliens (e.g., the “little green men” or “the grays”) envision alien species to be extremely homogeneous, virtual clones of each other. Therefore, in contrast to the human condition, aliens are typically assumed to be a biologically (and, sometimes, culturally) homogeneous population and, further, the implicit assumption seems to be that they have always been so; this homogeneity is the default condition of non-human sentient alien life. But what if this is not so?  What if alien species are characterized by similar racial and cultural diversity as are humans?  What could be the implications of that possibility for the Fermi paradox?

While controversial , evidence exists for genetic, hereditable differences in intelligence between human population groups, such as races . Behavioral differences exist as well  with some populations exhibiting traits more compatible with a highly disciplined technological civilization, as evidenced by the historical record of accomplishment . There is also a tendency for an inverse relationship between intelligence and reproduction .  This inverse relationship exists at the population level as well, as higher IQ populations of European and East Asian derivation have low birthrates and are demographically shrinking while the lower IQ populations of sub-Saharan Africa have higher birthrates and are expanding. In addition, mass migration typically occurs from regions of lower intelligence and accomplishment to those of higher intelligence and accomplishment. The expansion and migration of populations of lower intelligence, discipline, and accomplishment is, ironically enough, the result of conditions (e.g., higher standards of living, global communication, ease of travel) created by higher-intelligence populations. Extrapolating these trends forward suggests the possibility of a significant collapse of further development of, or even maintenance of, advanced technological human societies. In addition, varying cultures, established by different populations, can differ not only in their potential to develop the science and technology to achieve a space-faring civilization, but the interest and willingness to do so. Cultures may be more or less inclined toward homeostatic stability; homeostatic cultures would be less inclined to invest in the sustained technological development required of a space-faring civilization. Thus, differential cultural survival can also alter the technological trajectory of a civilization.

Further, technological advancement and the “global city” can create pathological social conditions akin to Calhoun’s rodent utopia experiments  with the resulting social pathologies that can contribute to societal collapse.  Related to this is the relaxation of natural selection in advanced societies.  Thus, we can observe dysgenic influences , not only manifested in decreased cognitive ability but in the development of “spiteful mutants” , maladaptive genotypes manifested in phenotypes that not only suppress the fitness of self but, spitefully, that of others, destroying social cohesion and promoting societal collapse. Such spiteful mutants are a biological result of technological advancement and the higher standards of living that relax natural selection against the unfit, and ironically contribute to the collapse of the technological society that spawned them.  Another social pathology, related to race and mass migration that can inhibit the development of a space-faring civilization is the erosion of trust, social cohesion, and the organic solidarity of society that has been associated with increased diversity .  

It is of course impossible to know how an alien species would react to increasing intra-species diversity even if such existed in their case, and we cannot assume their reaction would be the same as that of humans. Nevertheless, if we are going to extrapolate the human case to a possible mechanism explaining the Fermi paradox, then social disruption due to racial diversity also needs to be considered as a possibility. It is interesting that Wiley5 cites the idea that we need to be considering stellar societies rather than species; thus there may be cultural differentiation within a species, with each society being a separate contact possibility.  I would extend that in the negative sense, in that cultural (and biological!) differentiation into varying societies, followed by contact and migration between them, may induce pressures and pathologies that would reduce, and not expand, alien contact possibilities.

Therefore, if alien populations are characterized by similar types of diversity and selective pressures as humans, then the following may be a common scenario.  As a technological civilization develops, it creates dysgenic conditions that allows for the demographic expansion of less intelligent, less capable (racial) population groups, who replace the more intelligent and capable groups.  At the same time, dysgenic effects occur in all groups, decreasing intelligence and ability, while promoting spiteful mutants and social pathologies.  With the replacement of more capable racial groups with those less capable, and with the overall degeneration of all, any possibility of advancing to a technologically advanced, space-faring planetary (and then galactic) civilization is ended.  Furthermore, as these dysgenic influences spread, cultures that reject an increasingly unattainable planetary civilization replace the declining cultures that at one time dreamed of going to the stars. This can be outlined as follows:

1. An intelligent alien species evolves on its home world.

2. Similar to humans, this species is differentiated into different genetically and phenotypically varied races (subspecies). These races differ in intelligence, abstract thinking, behavioral traits, accomplishment, rates of reproduction, culture, etc.

3. As the more intelligent and accomplished racial groups produce technological advancement, the enhanced standard of living, and decreased selective pressures, have a variety of consequences.

4. Population growth of the less intelligent and accomplished groups increases and outpaces that of the more intelligent and accomplished groups. The latter may actual see stagnant or declining population and increasingly become replaced by migrants from the less intelligent and accomplished populations.

5. At the same time, dysgenic trends for all populations decrease global intelligence, increase numbers of “spiteful mutants,” and result in various social pathologies. Diversity would erode trust and social cohesion, making long term investment in major projects unfeasible. Scientific innovation, technological advancement, and economic development would all plummet.

6. In the midst of this chaos, cultures may prefer homeostasis over technological advancement and will in any case lose the capacity for such advancement.

7. The alien species loses, perhaps irreversibly, the capacity (and interest) for the development of a highly technologically advanced space-faring civilization.

To summarize the major thesis: there is a Gresham’s-type law of universal racial diversity. Thus, the more intelligent and productive races of any sentient species will be demographically outcompeted by those that are less intelligent and accomplished; the latter, despite their deficiencies, are inevitably more fit with respect to the ultimate criterion of survival.  Further, increased racial diversity among the alien civilization in territories previously important for innovation would induce a variety of disruptive social pathologies that would inhibit the pace of innovation. The threshold of technological competence for a detectable alien civilization would no longer obtain as the race or races capable of maintaining that civilization are replaced by those incapable. Therefore, no such civilizations are detected.

Further, one can link my hypothesis with that of Wong and Bartlett4 and state that one reason why planetary civilizations inevitably fail to solve their problems and collapse, or are forced into stasis, is precisely because the more intelligent fraction of the civilizational population are replaced by those less intelligent and less capable.  If the “race and IQ” problem is inevitable then that would make the sustainability problem inevitable as well.

Proving my theory is problematical; the same can be said of many other theories about the Fermi paradox.  Extrapolating from the human case to the alien is tempting, but is fraught with assumptions and speculations. The absence of alien contact does not specifically and definitively inform us to the reasons for that absence, leaving us with nothing but speculation. Ironically enough, or paradoxically enough, an answer to the paradox may involve actually finding the remains of an alien civilization and/or its artifacts, or somehow coming into contact with an extent civilization, and then, in some manner, discovering the civilizational trajectory of that species to discover what if anything went wrong. Obviously, the presence of racial differentiation in sentient alien life, with each race having different capabilities, would be compatible with this thesis.  Even more general, we would expect alien life to exhibit the types of genetic/phenotypic variation and processes of natural selection as life on Earth, with fitness ultimately being defined by reproductive capacity and genetic continuity.

Even if it was possible to obtain such information about sentient aliens, the data would be limited in sample size (even to a sample size of one) and its universal applicability would be in question.  For the time being, we are left with theory, hypothesis (with little immediate chance of testing/falsification), and speculation. Indeed, given the problems in testing/falsifying any of these ideas, they are more truly speculative theories than scientific hypothesis.  We are left to wonder.

Discussion

It may well be that some combination of some or all of the ideas listed above, including my own seven-point alternative hypothesis, may explain the Fermi paradox. Indeed, one book  listed fifty (!) possible explanations for the Fermi paradox (none blaming it on racial diversity); it is unlikely that any one of those, or mine for that matter, is the one and only answer.  Perhaps none of them are. The alien mind and culture may be so different from that of humans that they may eschew a space-faring technological civilization for reasons we cannot imagine and not those listed above.

We may never know the validity of the thesis outlined here, but its plausibility (at least in my opinion) should be a warning to us of the possibility of a similar situation happening to humanity. The pace of innovation, particularly of “disruptive” findings is slowing  and while there may be a number of reasons for this, and while correlation does not equal causation, there is a correlation between a slowing down of innovation and increasing racial diversity as well as with mass migration and the resulting multiculturalism in the West. It is at least possible that something similar has occurred to other sentient intelligent species.

I would argue that, in any case, humans had better solve these problems for themselves.  If my thesis is correct, then the current trajectory of humanity would preclude the development of a space-faring civilization. If the Hart-Tipler thesis is correct, then the fate of humanity is the fate of the only intelligent life in the galaxy/universe, and these issues therefore take on cosmic importance.  If intelligent alien life does exist, and if the Fermi paradox ends up being proven wrong, if contact is established, then it behooves humanity to be as technologically advanced as possible to deal with that eventuality. Regardless of the possibilities, from the standpoint of human interaction with the cosmos, current dysgenic trends must be stopped and reversed.  While such a suggestion, particularly with its implications, re: race and immigration, may be politically unpalatable in some quarters, the argument nevertheless must be made.

We may never know why THEY are not HERE, but we may discover why WE are not, and never will be, THERE.  And therein lies, perhaps, the true utility of these theories. 

References

1. Robert H Gray 2015. The fermi paradox is neither Fermi’s nor a paradox. Astrobiology 15(3):195-9. doi: 10.1089/ast.2014.1247.  

2. Michael Hart. 1975. “An explanation for the absence of extraterrestrials on earth.” Q. Jl R. astr Soc. 16: 128-135.

3. Frank Tipler. 1980. “Extraterrestrial intelligent beings do not exist.” Q. Jl R. astr Soc. 21: 267-281.

4. Michael L. Wong and Stuart Bartlett. 2022. “Asymptotic burnout and homeostatic awakening:  a possible solution to the Fermi paradox? J. R. Soc. Interface 19: 20220029. https://doi.org/10.1098/rsif.2022.0029.

5. Keith B. Wiley. 2011. “The Fermi Paradox, Self-Replicating Probes, and the Interstellar Transportation Bandwidth” arXiv:1111.6131 [physics.pop-ph]m(or arXiv:1111.6131v1 [physics.pop-ph]). https://doi.org/10.48550/arXiv.1111.6131.

6. F. Drake. 1965. “The radio search for intelligent extraterrestrial life.: Curr. Aspects Exobiol. 32: 323. Doi:10.1016/B978-1-4832-0047-7.50015-0).

7. Milan M. Ćirković and Branislav Vukotić. 2008. “Astrobiological Phase Transition: Towards Resolution of Fermi’s Paradox. Origins of Life and Evolution of Biospheres” 38: 535–547 doi: 10.1007/s11084-008-9149-y

8. Heiner Rindermann, David Becker, and Tomas R. Coyle. 2020. “Survey of expert opinion in intelligence: Intelligence research, experts’ background, controversial issues, and the media.” Intelligence. 78: 101406 https://doi.org/10.1016/j.intell.2019.101406.

9. Jordan Lasker, Bryan J. Pesta, John G.R. Fuerst, and Emil O.W. Kirkegaard. 2019. “Global ancestry and cognitive ability.” Psych 1: 431-459. doi:10.3390/psych1010034.

10. Tomás Cabeza de Baca, and Michael Anthony Woodley Of Menie. 2018. “Lynn’s r/k selection theory of criminality revisited: Consideration of individual differences and developmental life history contributions to the patterning of population differences in antagonistic social strategies.” J Crim Justice 59:87-91. doi: 10.1016/j.jcrimjus.2018.05.009. PMID: 31363234 PMCID: PMC6667178 DOI: 10.1016/j.jcrimjus.2018.05.009.

11. Charles Murray. 2003. “Human Accomplishment: The Pursuit of Excellence in the Arts and Sciences, 800 B.C. to 1950.” HarperCollins ISBN 006019247X.

12. Satoshi Kanazawa 2014. “Intelligence and childlessness” Soc Sci Res 48:157-70.  doi: 10.1016/j.ssresearch.2014.06.003.

13. John B. Calhoun. 1962. “Population density and social pathology.” Scientific American 206 (2) 139-149.

14. J. C. Loehlin. 1997. “Dysgenesis and IQ: what evidence is relevant?” American psychologist. 52 (11) 1236-1239. Doi/10.1037/0003-066X.52.11.1236.

15. Edward Dutton. 2022. “Spiteful Mutants: Evolution, Sexuality, Religion, and Politics in the 21st Century.” Radix.

16. Robert D. Putnam 2007. “E pluribus unum: diversity and community in the twenty-first century the 2006 Johan Skytte prize lecture.” Scand. Polit. Stud. 30, 137–174. doi: 10.1111/j.1467-9477.2007.00176.x.

17. Stephen Webb. 2002.’Where is everybody? Fifty solutions to the Fermi’s paradox.” Copernicus, New York.

18. Michael Park, Erin Leahey, and Russel J. Funk. 2023. Papers and patents are becoming less disruptive over time. Nature 613, 138–144 (2023). https://doi.org/10.1038/s41586-022-05543-x.

Biological Race from 2008

Reality of race.

PLoS Genet 2008 Dec;4(12):e1000294.

doi: 10.1371/journal.pgen.1000294. Epub 2008 Dec 5.

Effects of cis and trans genetic ancestry on gene expression in African Americans

Alkes L Price, Nick Patterson, Dustin C Hancks, Simon Myers, David Reich, Vivian G Cheung, Richard S Spielman

PMID: 19057673 PMCID: PMC2586034 DOI: 10.1371/journal.pgen.1000294

Link to paper. Excerpts, emphasis added:

Abstract

Variation in gene expression is a fundamental aspect of human phenotypic variation. Several recent studies have analyzed gene expression levels in populations of different continental ancestry and reported population differences at a large number of genes. However, these differences could largely be due to non-genetic (e.g., environmental) effects. Here, we analyze gene expression levels in African American cell lines, which differ from previously analyzed cell lines in that individuals from this population inherit variable proportions of two continental ancestries. We first relate gene expression levels in individual African Americans to their genome-wide proportion of European ancestry. The results provide strong evidence of a genetic contribution to expression differences between European and African populations, validating previous findings. Second, we infer local ancestry (0, 1, or 2 European chromosomes) at each location in the genome and investigate the effects of ancestry proximal to the expressed gene (cis) versus ancestry elsewhere in the genome (trans). Both effects are highly significant, and we estimate that 12+/-3% of all heritable variation in human gene expression is due to cis variants.

Author Summary

Variation in gene expression is a fundamental aspect of human phenotypic variation, and understanding how this variation is apportioned among human populations is an important aim. Previous studies have compared gene expression levels between distinct populations, but it is unclear whether the differences that were observed have a genetic or nongenetic basis. Admixed populations, such as African Americans, offer a solution to this problem because individuals vary in their proportion of European ancestry while the analysis of a single population minimizes nongenetic factors. Here, we show that differences in gene expression among African Americans of different ancestry proportions validate gene expression differences between European and African populations. Furthermore, by drawing a distinction between an African American individual’s ancestry at the location of a gene whose expression is being analyzed (cis) versus at distal locations (trans), we can use ancestry effects to quantify the relative contributions of cis and trans regulation to human gene expression. We estimate that 12±3% of all heritable variation in human gene expression is due to cis variants.

So, it had been previously found that cells derived from different human populations (cough, races, cough) differ in gene expression, but the fallback position was that this all could have been from non-genetic (e.g., environmental) causes. These authors reasoned that an admixed population could be used to tease out genetic vs. non-genetic causes for differences in gene expression, as the former would alter gene expression in line with variation in the proportion of different ancestries.  African-Americans, modeled as a mix of CEU (European) and YRI (sub-Saharan African) ancestry was used.  The data confirms that a portion of the differences in gene expression between CEU and YRI are due to genetic, heritable differences in ancestry.  This (my statement here) absolutely confirms the biological basis of race and that differences in racial ancestry influences gene expression.  The authors also looked at how much of these genetic influences on gene expression were due to genes in cis (proximal to the expressed gene) or trans (ancestry derived from elsewhere in the genome).  Only ~ 12% was cis, demonstrating (my statement again) the importance of trans-related genetic epistasis and of genetic structure on the differentiation of human populations.

Introduction

Several recent epidemiological studies in African Americans have taken advantage of this, showing that many phenotypic traits vary with the proportion of European ancestry [3]–[5]. Here, we apply this idea to analyze population differences in gene expression.

Gene expression is a fundamental determinant of cellular phenotypes, and understanding how gene expression variation is apportioned among human populations is an important aspect of biomedical research, as has been true for apportionment of human genetic variation at the DNA level [6]. Recently, four studies analyzed lymphoblastoid cell lines from HapMap samples and reported that a large number of expressed genes exhibit significant differences in gene expression among continental populations [7]–[10]. However, results of these studies may be affected by non-genetic factors such as differences in environment, differences in preparation of cell lines, or batch effects [2],[9],[11],[12]. In particular, a recent review article has suggested that much of the expression variation across populations is caused by environmental factors [13]. On the other hand, analyses of expression differences that are correlated to ancestry within an admixed population are robust to all of these concerns.

In this study, we analyzed lymphoblastoid cell lines from 89 African-American samples and investigated the relationship between expression levels of ∼4,200 genes and the proportion of European ancestry. We compared the results with those predicted from the differences in expression levels between 60 European samples (CEU from the International HapMap Project) and 60 African samples (YRI from HapMap) [6]. We confirmed the existence of heritable gene expression differences between CEU and YRI by showing a highly significant correspondence between observed CEU vs. YRI differences (i.e. differences between sample means) and the expression differences predicted by ancestry differences among African Americans. 

Thus, we see the main point – by assaying how gene expression in African Americans differs based on European vs. African ancestry, they demonstrated a highly significant effect of genetic ancestry, on the population level, to gene expression differences between Europeans and Africans. 

Although it needs to be formally demonstrated, I assume the same applies to differences between other pairs of racial groups, and may well apply (to a perhaps lesser degree, dependent on genetic differences and kinship overlap) between ethnic differences within a race.

Notably, the correspondence holds regardless of whether differences between CEU and YRI are large or small. This suggests that the effects of heritable population differences on variation in gene expression are widespread across genes, mirroring population differences at the DNA level [6].

It is a general effect, and not restricted only to genes with large differences in inter-population expression.

Heritable variation in gene expression may be due to cis or trans variants. Previous studies in humans have been successful in mapping both cis and trans effects, but the results they provide are far from complete, due to limited sample sizes [14], [15], [9], [16]–[20]. In particular, the relative number of cis vs. trans associations that were reported varies widely across these studies, perhaps due to differences in power or choices of significance thresholds [13]. Thus, the overall extent of cis vs. trans regulatory variation in human gene expression has not yet been established. Here, by measuring how gene expression levels across all genes vary with local ancestry (0, 1 or 2 European chromosomes) either proximal to the expressed gene (cis) or elsewhere in the genome (trans), we estimate that 12±3% of heritable variation in human gene expression is due to cis variants.

The relevance of this was explained above.

Results

This suggests that the ancestry of the AA samples might be reasonably approximated as a mixture of varying amounts of CEU and YRI ancestry, as reported previously [21]. 

We estimated the genome-wide proportion of European ancestry for each the 89 AA samples (see Materials and Methods). Genome-wide ancestry proportions varied from 1% to 62% with a mean±SD of 21±14%; this ancestry distribution is similar to that in other AA data sets [21],[25]. Genome-wide ancestry estimates were strongly correlated (r 2>0.99) with coordinates along the top principal component (eigenvector with largest eigenvalue) (Figure 1).

We investigated whether the correspondence between observed CEU vs. YRI gene expression differences and expression differences due to ancestry among AA is concentrated in genes with large differences between CEU and YRI. If only a fraction of genes were truly differentiated, as suggested by previous studies, then genes with large observed CEU vs. YRI differences would be more likely to be truly differentiated and would show stronger validation in AA. For example, when we simulated a mixture model in which c = 0.43 for the set of all genes but only 50% of genes are truly differentiated between CEU and YRI, we obtained a larger value of c = 0.53 for genes in the top 10% of observed CEU vs. YRI differences (see Text S1). However, Figure 2 shows no evidence of nonlinear effects. Indeed, we recomputed c using only genes in the top 10% of the magnitude of observed CEU vs. YRI differences, and obtained c = 0.44, which is similar to the value of 0.43 using all genes. These results suggest that population differences in gene expression are not restricted to a fraction of genes but in fact are widespread across genes, mirroring population differences at the DNA level [6].

Effects of cis versus trans Ancestry on Gene Expression in African Americans

The effect of ancestry on gene expression in African Americans may be due either to variation in regulatory variants proximal to the gene (cis) or to variants elsewhere in the genome (trans)…

…We estimate the proportion πcis of heritable gene expression variation between Europeans and Africans that is due to cis variants as ccis/(ccis+ctrans) = 12%, with a standard error of 3%…Thus, population variation does not appear to differ for cis vs. trans effects, implying that our estimate of πcis = 12±3% applies to all heritable variation in human gene expression.

Discussion

We have shown how phenotypic variation in an admixed population can be coupled with variation in ancestry to shed light on differences between ancestral populations; our approach makes no assumptions about the population histories underlying the differences between the ancestral populations. We have applied this approach to gene expression in African Americans and shown that observed population differences (differences in sample means) between CEU and YRI in gene expression correspond, with overwhelming statistical significance, to differences among African Americans of varying ancestry, implying a substantial heritable component to the population differences. In reaching this conclusion via analysis of an admixed population, we eliminate confounding with non-genetic contributions to observed differences between the ancestral populations, which could result from differences in environment, differences in preparation of cell lines, or batch effects. The value of 0.43 for the “validation coefficient” c implies that both genetic and non-genetic effects contribute to observed population differences between CEU and YRI.

The politically correct default assumption that it is all non-genetic is therefore refuted.

Going forward, admixed populations will continue to be useful for understanding and mapping gene expression and other phenotypes.

Indeed.

That this was demonstrated back in 2008 and yet people – including high-ranking academics – continue to argue against a biological basis for race tell us how much STEM (particularly genetics/population genetics) has been politicized.  The System/Left has been lying to you.

Is Biological Whiteness a Dangerous Concept?

Astonishing.

So-called “White nationalist” Greg Johnson writes (emphasis added):

Greg JohnsonJune 22, 2023 at 1:00 am

This is why biological whiteness is a dangerous concept for nationalists. You don’t seem to think that replacement migration into Switzerland is a problem if the replacers are biologically white. I think it is a problem, because Switzerland should be the homeland of the various Swiss communities. In short, from a nationalist point of view, all white people are not equal or fungible. Replacing the Swiss with people from the Balkans and Iberia is still a problem.

First, just because one Counter-Currents commentator implied that such fungibility exists does NOT mean that this is a position held by most  pan-Europeanlsts. Second, it is simply astonishing that a so-called “White nationalist” states in writing that “biological whiteness is a dangerous concept for nationalists.” Hey Strom and Williams, did you read that? WN 3.0 on the march! Can’t have that “biological whiteness” getting in the way of Our Man in Arkansas. Third, how about replacing Hungarians with the likes of John Morgan? Any comments about that?

Let us consider this in more detail.  If “biological whiteness” is so bad that it is a “dangerous concept” for “nationalists” then what are the implications for European-derived peoples?  That comment suggests that different European ethnic groups should be considered disjunctive entities, as alien to each other as they would be to Asians and Africans. It means that mating between European ethnic groups should be considered miscegenation and that persons of mixed European descent are multiracial, and it means there is no more rationale for cooperation between Europeans than between Europeans and, say, Chinese or Indians.

Am I being unfair?  All Johnson had to write was that Whites are not fungible and that ethnic uniqueness – at least in Europe itself – should be preserved. But this person, with a background in philosophy, with a PhD, who is the editor of Counter-Currents, who has written books, and who is styled to be a “leading intellectual of the Dissident Right” specifically chose to write that “biological whiteness is a dangerous concept for nationalists.”  Those words have an obvious meaning and that meaning is not simply “let’s preserve ethnic groups.” It is instead a direct public attack against the deep meaning and value of biological whiteness and the deep ancestral connections between Europeans; it is an intentional devaluation of biological race in favor of a narrow petty nationalist focus on individual ethnic groups. Sometimes a cigar is just a cigar and sometimes we just need to accept statements at face value without trying to parse them. If a PhD in philosophy, a book author, a website editor, writes that “biological whiteness is a dangerous concept” then we must take them at their word. Therefore, the implications of the statement are self-evident and my comments are not unfair.

I go on record here as unequivocally denouncing Johnson’s comment.  Will others in the Dissident Right do the same?  Taylor, MacDonald, Strom, Williams, “Hood” and all the rest? What say you?

I say that anyone who does not publicly denounce Johnson’s comment should be considered as tacitly endorsing it.  And any person who continues to positively interact with Johnson and Counter-Currents after this should be associated with that comment and its implications.

I have repeatedly warned all of you about Counter-Currents and its attempts to redefine White nationalism, and I have warned you about WN 3.0, HBD, etc. and I have been ignored.  Now the chickens are coming home to roost – a “movement” “leader” has declared that “biological whiteness is a dangerous concept.”  Blame yourselves for enabling and supporting that.

Evolution of Prejudice

McGregor article.

See here.  Download here. Selected excerpts (bold font emphasis added) with my comments:

The author examines the phenomenon of ‘prejudice’ and explains the possibility that its roots are not purely cultural. The proclivity for prejudice appears to be deeply rooted in the human psyche, and has been shown to be of distinct utility in furthering the process of speciation.

That makes sense given the arguments made in the article, which follow a reasonably logical chain of thought. Genetic isolation is required for speciation, and if “prejudice” enables such isolation, then, obviously, an ecosystem favorable to speciation will be created.

The sociobiological nature of ‘prejudice’ can only be clearly understood if we realize that the emotional tensions generated when diverse ethnic groups are forced into close geographical contact do not derive solely from contrasting cultural systems: they reflect deeply ingrained sociobiological mechanisms which serve an essential evolutionary function. Indeed, they are by no means of modern or even recent origin in the history of our species.

Fair enough.

Evolution reveals two major trends, the first of which is a trend from the simplicity of unicellular life forms to the complexity of advanced organisms such as are represented by mammals, primates and men. The second is the trend from the primitive uniformity of early life forms to the rich variety of diverse species, sub-species, or, in the case of man, the diverse races which today inhabit the earth. 

That is an important point, which well summarizes the two major strands of evolutionary direction. First, we observe increased complexity, although of course many of the simpler life forms are still with us today.  Second, we observe an increasing diversity of life.  The two points are correlated; in the beginning there were only the simpler life forms (simplicity and uniformity – “primitive uniformity”) and today we have a diversity of life forms, adding the complex to the simple.  And, today, both simple and complex are characterized by that diversity, including the ethnic and racial diversity we see today.

…the higher more mobile forms of life require other defenses to prevent the accidental hybridization of evolving sub-species. Clearly, the evolutionary process would be frustrated if every new biological or evolutionary experiment, each new phylogenetic continuum, sub-species or race, were to lose its novel and distinctive combination of genes by admixture with sibling populations, or by the reabsorption of divergent sibling populations into the parental stock. In short, during the period in which emerging sub-species are evolving into separate species – so different from each other that they no longer have the biological ability to crossbreed their genetic identity must be protected from crossbreeding by some form of barrier, either geographical or psychological, which will effectively prevent the negation of nature’s experiments before they can even emerge as separate species and subspecies.

That is all reasonable, but see what I write below about where to draw the line, as well as the benefits of diversification by creating new ethnies through stabilized blends of related parental ethnies of the same broad race, as long as the parental stocks are also maintained.  Such processes can create increasingly diverse “biological experiments” for the forces of evolution to work on.  One note – some species can interbreed and in some cases produce fertile offspring. Species differentiation is more of a genetic and phenotypic distance; true, in most cases there is a breeding barrier, but not always.

When such mechanisms have developed and the prevention of interbreeding is more or less complete, we are dealing with separate species. A race becomes more and more of a “concrete entity” as this process goes on; what is essential about races is not their state of being but that of becoming. But when the separation of races is complete, we are dealing with races no longer, for what have emerged are separate species.

This is consistent with Strom’s assertion that racial purity is something we should strive for as we move toward the future, not some past state of grace that we mourn as lost. Races are not static, they are “becoming” not “being.”  That is consistent with Salter’s ethnic genetic interests concept, which allows for replacement of maladaptive alleles and understands that even a genetically isolated population will change over time.

However, Dobzhansky continued: …. “Races and species as discrete arrays of individuals may exist only so long as the genetic structures of their populations are preserved distinct by some mechanisms which prevent their interbreeding. Unlimited interbreeding of two or more initially different populations unavoidably results in an exchange of genes between them and a consequent fusion of the once distinct groups into a single greatly variable array. A number of mechanisms encountered in nature (ecological isolation, sexual isolation, hybrid sterility, and others) guard against such a fusion of the discrete arrays and the consequent decay of discontinuous variability. The origin and functioning of the isolating mechanisms constitute one of the most important problems of the genetics of populations.”

As Dobzhansky added, genetic isolation becomes “advantageous for species whose distributions overlap, provided that each species represents a more harmonious genetic system than the hybrids between them.”

See the Udry paper on the health and behavior risks of mixed-race adolescents.  While there may be a variety of reasons for those problems, genetic mechanisms may be included among them. This, there may be outbreeding depression, disrupting the “more harmonious genetic system” of unmixed individuals, including disruption of coadapted gene complexes and the epistatic interactions between genes that influence phenotype.

But geographical separation is not always effective in the case of the more advanced mobile forms of animal life, and various “feral restraints” also customarily evolve to discourage cross-breeding on those occasions that individuals from divergent populations do chance to meet. These feral restraints serve a vital evolutionary process. Zoologists have identified two types of such constraints, the first of which are called – “built-in” constraints, based upon physical sign stimuli. “Built-in” physical constraints may take the form of distinctive shape, color, smell, or even patterns of movement, common to animals of the same subspecies, but absent from other populations…Such distinctive characteristics serve as a warning to members of related but disparate subspecies not to attempt sexual relationships. They are like a sign that reads “Danger! a new biological experiment is in progress. Do not approach!”

Different hominid types can be said to have characteristics than can trigger “built in constraints” although obviously this is an attenuated reaction given the amount of miscegenation that occurs.  Still, in many cases, there is a repulsion, an aversion, to the phenotypes of radically different hominid types.

Such distinctive characteristics serve as a warning to members of related but disparate subspecies not to attempt sexual relationships. They are like a sign that reads “Danger! a new biological experiment is in progress. Do not approach!” (Simpson, 1964). But in addition to these built-in constraints, the distinguished zoologist, Peter Klopfer, (1970) has shown that acquired constraints exist among feral animals due to behavioral imprinting. These may be equated with the culturally-reinforced prejudices associated with “in-group” and “out- group” behavior among human beings.

Culture is important.  Proximate interests affect ultimate interests (and vice versa).

Domestication, by breaking down territorial restrictions and destroying patterns of feral or natural activity, often results in perverted, misdirected, unnatural and anti-evolutionary behavior… Culture, particularly in urbanized societies, may likewise pervert human instincts by suppressing natural feral constraints and encouraging abnormal patterns of behavior, leading to similar distortions of normal biological behavior, such as homosexuality and the quest for abnormal erotic experiences, including those associated with inter-subspecific sexual experimentation. 

We definitely observe this occurring, particularly in and around the urban areas of highly developed majority White nations.

No human civilization has to date avoided collapse, and it is tempting to enquire whether social conditions which diverge too widely from the natural or feral conditions under which mankind evolved – and to which humankind is biologically adapted – may weaken the survival potential of overdomesticated populations by promoting anti-evolutionary life-styles, together with their concomitant reproductive abnormalities.

This overdomestication – that may also influence what Frost calls genetic pacification – no doubt contributes to these issues. The bizarre behaviors observed in “mouse utopia” experiments may well have their human counterparts.

Indeed evolution is concerned not with the individual organism but only with breeding populations, with phylogenetic continua. Evolution involves populations, sub-species and species. Evolution is in no way concerned with the welfare or well-being of any one individual organism except to the extent that the death or survival of that organism may affect the gene pool of the breeding population. 

I suppose that many academics – those who reject group selection – would disagree with that.  I think here that McGregor goes too far in dismissing the importance of the individual.  Genetic interests run along the continuum from self-family-ethny-humanity.  I agree though that group interests are typically ignored by mainstream evolutionary theorists,

Fitness also must not be misunderstood. In the evolutionary context – by which we mean the living reality – fitness means only the ability of any breeding population, sub-species or race to reproduce itself, and, at the more complex mammalian, primate and human levels, the ability of adults to protect their offspring until the offspring can in turn successfully reproduce themselves. 

True. People always confuse adaptive fitness with some subjective valuation of phenotypic traits. Genetic continuity of sickly retardates makes them more fit than sterile supermen.

Biologically, an individual is little more than a link in the chain of generations. The genetic integrity of the gene pool is therefore of paramount evolutionary importance. Evolution could not continue its work amongst the higher animals if each new experimental sub-species were to lose its identity before it had time to evolve into a new species.

More or less true, as long as we do not completely dismiss individual interests

Evolutionary competition is between rival sub-species…cooperation at the primate and human level is aimed more at group survival than individual survival…

Group selection.

The genetic advancement of man arose as a result of ongoing competition for survival between genetically different, non-interbreeding hominid populations, and was sustained not merely by geographical isolation but also by developing bonds of cooperation and love within the kindred, and of suspicion, fear, antagonism, and even warfare against such alien groups as might become competitors for the territorial and material resources necessary to sustain life…the evolutionary struggle is commonly fiercest between closely related species, and particularly between sub-species who are dependent on and consequently competing for similar resources…

At some point though, when very closely related group compete (and if there is kinship overlap between them then this probably becomes worse) they may harm each other’s interests and benefit genetically more distant third parties.  Here, I refer to intra-European conflict and the consequent benefit to the world of Color. Having the conflict at the broad racial level seems to be the best balance if group interests.

…these two separate sets of behavior as syngenism (attachment and loyalty) and ethnocentrism (suspicion of aliens). He further suggested that the pressure of competition from other groups tended to reinforce the feelings of loyalty and cooperation, heightening the consciousness of ethnocentrism and prejudice against “outsiders.” 

But see my work on Racial Proximity Theory and how ethnocentrism against highly related groups (“narcissism of small differences”) can be counter-productive.

These forces enhance the competitive viability of the group in its struggle to survive and to outbreed rival groups, and also serve to protect the ongoing process of homogenization within the group’s own gene pool – a process which is itself dependent upon a high degree of genetic isolation.

That is reasonable.

These attitudes of in-group loyalty and out-group suspicion, which appear to have evolved long before the evolution of primitive human bands and to have developed more consciously identifiable forms at the level of tribal and national societies, reflect a clearcut evolutionary purpose. Patterns of racial and ethnic prejudice, of in-group loyalty and out-group suspicion, have served an effective evolutionary purpose over the long history of primate and human biological evolution, both in enhancing the competitiveness of the individual breeding population and also in preserving the uniqueness of its distinctive genetic heritage by discouraging interbreeding with the members of disparate subspecies. 

The only caveat I have to all of this is a point I have made previously, in that hybrids of (relatively) closely related ethnies can form new stabilized blends over time and become their own new ethny lines, just as some dog breeds are blends of older stocks (e.g., the bullmastiff). From the human perspective, it will be important to make sure that the original ethnic stocks are maintained and that the blending creating new strains only takes place within the same race (e.g., among Europeans). This creation of new stocks can be part of the diversification of life, and as long as the original strains are maintained, the evolutionary striving can continue. Of course as well, I do not believe we would want speciation among Europeans; however, between races is a quite satisfactory conclusion. It depends where you draw the line at “disparate subspecies.”  The major human races definitely qualify.  Of course, every individual or group has the right to make narrower choices if they wish.  And if some want to inter-breed across wide genetic lines – a broader choice – they can do so, but in a different territory. Here, I am speculating on what is likely the best choice in a White state.

The evolutionary message is clear. Human groups which lose their internal sense of identity and cohesion in respect of other groups eventually cease to exist as discrete realities. Amongst the higher more mobile forms of animal life, isolating mechanisms such as prejudice are necessary to preserve the genetic identity of races and sub-species (as emergent species) by inhibiting miscegenation. A human population which practices endogamous marriage and strives to preserve the integrity of its gene pool should not be criticized as immoral. Such behavior implies that it is adhering to deeply rooted instincts essential to the evolutionary process, which process – from the point of view of purely logical, naturalistic thought – provides the only basis for any scientifically sound system of ethical philosophy.

I agree with that ethical sentiment, and it is completely compatible with Salter’s ethnic genetic interests and universal nationalism.  Although McGregor seems to promote what Salter might call the “pure ethic” – putting biological requirements over all other interests.  These ethical issues require continued consideration.

Note: If humans ever colonize space, it is possible that the geographic isolation there would enable speciation as well.